
<a href="https://reason.com/2025/07/24/a-beatnik-tourist-in-ayahuasca-country/" target="_blank">View original image source</a>.
Imagine embarking on a journey seeking spiritual enlightenment only to be met with questionable food, grumpy locals, and multiple robberies. That’s exactly what Beat legend William Burroughs faced during his 1953 trip to South America. His book, The Yage Letters, captures his hilarious and cynical commentary on the ayahuasca experience and the people he met along the way. Spoiler alert: a Bolivian Trotskyite and dubious medicine men feature prominently in this comedic travelogue.
Burroughs, known for his hard-boiled writing style, doesn’t hold back in sharing the less-than-glamorous aspects of his journey. He vividly describes his physical reactions to ayahuasca—let’s just say they weren’t the cosmic revelations most dream of. Instead, he offers tales of collapsing in discomfort and shockingly ordinary insights about local culture and politics. Who knew enlightenment came with a side of malaise?
What’s refreshing in Burroughs’ letters is that amid the grumbling, he occasionally finds joy in the culturally rich tapestry of South America. Reading about his temporary love for the mestizo blend of the population is almost uplifting until he is robbed—twice. The man can’t catch a break, can he?
If you’ve ever traveled for enlightenment—or even just good food—only to find yourself in a bit of a comedic pickle, you might resonate with Burroughs’ misadventures. So, was the search for enlightenment worth the chaos? What’s the most bizarre thing you’ve encountered on your own adventures?
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